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science
Evidence supporting a catalytic pentad mechanism for the proteasome and other N-terminal nucleophile enzymes
Proteases are defined by their nucleophile but require additional residues to regulate their active sites, most often arranged as catalytic triads...
nature.com - 10 days ago

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nature
Scientists expect more drought this year in parts of the Midwest and Great Plains
Farmers and ranchers getting ready for planting season might also need to prepare for another year of drought. Some parts of the Midwest and Great...
wglt.org - 9 days ago
parenting
Personalient individuals are happier due to smoother social relations
More “personalient” individuals—those with higher levels of the General Factor of Personality (GFP)—are generally happier, according to research...
psypost.org - 30+ days ago
space
Why is one half of Mars so different to the other? ‘Marsquakes’ may have just revealed the answer
Mars is home to perhaps the greatest mystery of the Solar System: the so-called Martian dichotomy, which has baffled scientists since it was...
theconversation.com - 30+ days ago
music
Warren Haynes Pens Eulogy For The Band's Garth Hudson: "The Last Piece Of The Puzzle Is Gone" [Video]
Warren Haynes is best known for his accolades as a guitarist, vocalist, songwriter, and bandleader for acts like Gov’t Mule, the Allman Brothers Band,...
liveforlivemusic.com - 30+ days ago
job & work
Cuban actor Erdwin Fernández: "In Miami, there were those who turned their backs on us."
The actor stated that many supported him upon arriving in Miami, while others denied him employment in the artistic sector. He is now acting on...
cibercuba.com - 30+ days ago
beauty
Allergies Might Explain Why Your Dog's Paws Are Bothering It
Allergies in dogs have become a common issue that many pet owners face. While there is limited research into the topic, a 2021 study by Universidade...
cuteness.com - 25 days ago
apps
The Third iOS 18.4 Beta Is Out Now, but Maybe Wait to Install It on Your iPhone
Why it's smart to not jump on the latest prerelease iPhone software. Apple is moving quickly on updating the beta versions of its software for the iPhone and its other devices. The third iOS 18.4 public beta is out now, with improvements to Apple Intelligence and features such as brand-new emojis...
cnet.com - 24 days ago
pets
Woman Raises Panther Mistaking It For A Kitten
Bizarrely, a woman became a surrogate mother to a baby panther. She mistook it for an ordinary kitten! Meanwhile, her loyal Rottweiler didn’t mind...
animalsaroundtheglobe.com - 30+ days ago
beauty
Grammys 2025: Gracie Abrams' 'Silk Ballerina Nails' Are Perfect
Brides, take note. If CHANEL’s Ballerina polish sounds familiar, it is thanks to another Grammy nominated musician and actress, Selena Gomez. The Rare...
newbeauty.com - 30+ days ago
health
Unlocking AI’s Potential in Healthcare — A Semantic Foundation - MedCity News
AI is revolutionising healthcare — enhancing diagnostics, streamlining workflows and supporting medical professionals in unprecedented ways. But with...
medcitynews.com - 30+ days ago
music
A 74-Year-Old Musician Makes a Million a Year From an Unpopular Song Written Nearly 50 Years Ago. Here's How.
The song never became a Billboard hit but proved extremely lucrative for its writer. If you went back in time and asked composer and musician Mark Mothersbaugh to predict what his biggest moneymaker would be in his nearly 50-year career, he would not have said "Uncontrollable Urge." The now...
entrepreneur.com - 30+ days ago
cycling
City plans to create waterfront greenway connecting Long Island City to Bayside
Ben Turner enjoys biking on the Little Bay Park bike path in Bayside. Soon, he may be able to extend his ride to Long Island City, on the other side...
ny1.com - 11 days ago
sports
UFC 317: Huge New Fight Added To International Fight Week Card– Report
When Manel Kape defeated Asu Almabayev on March 1, he thought he did enough to earn another shot at Alexandre Pantoja and the UFC men's flyweight title. As it turns out, it appears he's landed a tough title-eliminator fight with the No. 1 contender in the division, Brandon Royval. According to...
forbes.com - 1 day ago
science
Bird Flu Virus Can Survive in Raw Milk Cheese for Months, Study Finds
While health authorities have advised against drinking raw milk because it can harbor the bird flu virus and other pathogens, health risks from...
verywellhealth.com - 15 days ago
cycling
Lotte Kopecky calculating explosive Poggio attack, hair-raising descent in hunt for another Monument victory at revived Milan-San Remo
Lotte Kopecky made a deliberate decision to delay the start of her season to place a firm target on Milan-San Remo and a few of the major Spring...
cyclingnews.com - 15 days ago
outdoors
Patagonia's Winter Sale is here: Save up to 40% on jackets, vests, sweaters, bags and other gear
If the weather has been exceptionally cold, wet and gray where you're at, here's some welcome news: Patagonia's annual Winter Sale is now on, with deals on outdoor gear like waterproof jackets, down-filled parkas, roomy bags and packs and much more. Now, for a limited time , you can save on...
aol.com - 30+ days ago
job & work
Ohio State tops U.S. News 2025 online program rankings for Ohio schools
CLEVELAND, Ohio — In the hybrid working and learning world brought on by the pandemic, online degrees have become another tool for students seeking...
cleveland.com - 30+ days ago
cool stuff
How the Ringling Brothers Turned Sarasota Into a Circus Town
How John Ringling transformed Sarasota from a quiet fishing village into the world’s circus capital. Listen and subscribe on Stitcher, Apple Podcasts,...
atlasobscura.com - 30+ days ago
money
Emily Scarratt: ‘Retirement looked like the only option – but I’ve got another shot’
Eyes scanning the memorabilia decorating the space around her, Emily Scarratt is surrounded by evidence of the progress made and the progress still...
independent.co.uk - 14 days ago
health
How to have conversations with people who fall for misinformation this election campaign
Canadians head to the polls on April 28. Like other recent general elections, both in Canada and around the world, this federal election campaign is...
theconversation.com - 12 days ago
lifestyle
Still need a Mother's Day gift? This 'stunning' 50" 4K smart TV is $ 160 off on Amazon
Stream more than 700,000 movies and TV episodes with this "user-friendly" device. Father's Day is around the corner (June 16), which means it's time...
yahoo.com - 30+ days ago
business
Council Post: Marketing Your Agency Like A Client Is A Growth Imperative
Chintan Shah is the President and Managing Partner at KNB Communications, a multi-award winning health + biotech marketing and PR agency. We’re all familiar with the saying about the cobbler’s children not having any shoes. It’s a common vocational contradiction—those who deliver excellence to others...
forbes.com - 3 days ago
learning
Reflections on Evidence-Based Grading Practices: What We Learned for Next Year
• Key lessons from schools implementing evidence-based grading practices. • How schools are overcoming common challenges, including building teacher and...
edweek.org - 10 days ago
health
What older adults need to know about concussions
The word “concussion” may bring to mind football players and other athletes. Or maybe someone who’s been in a bad car wreck. But the truth is that a concussion isn’t always the result of a severe impact. In fact, the most common cause of concussion is a fall. Which means older adults are more...
aol.com - 13 days ago
food & drink
Starbucks Sunsera Blend has a flavor that shines brightly
While many people have their preferred coffee order, others prefer to switch that roast depending on the season, situation, or even just by whim....
foodsided.com - 30+ days ago